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KMID : 0545120150250081321
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Journal of Microbiology and Biotechnology
2015 Volume.25 No. 8 p.1321 ~ p.1323
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Immune Regulatory Effect of Newly Isolated Lactobacillus delbrueckii from Indian Traditional Yogurt
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Hong Yi Fan
Lee Yoon-Doo
Park Jae-Yeon
Jeon Bo-Ram
Deepa Jagdish
Jang Soo-Jin
Chung Dae-Kyun
Kim Han-Geun
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Abstract
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Lactic acid bacteria (LAB) are microorganisms that are believed to provide health benefits. Here, we isolated LAB from Indian fermented foods, such as traditional Yogurt and Dosa. LAB from Yogurt most significantly induced TNF-α and IL-1β production, whereas LAB from Dosa induced mild cytokine production. After 16S rRNA gene sequencing and phylogenetic analysis, a Yogurt-borne lactic acid bacterium was identified and classified as Lactobacillus delbrueckii subsp. bulgaricus, and it was renamed L. delbrueckii K552 for the further studies. Our data suggest that the newly isolated L. delbrueckii can be used for the treatment of immune deficiency disorders.
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KEYWORD
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Lactic acid bacteria, Lactobacillus delbrueckii, Tumor necrosis factor-alpha, Interleukin-1beta, Indian fermented foods
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